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Managing GLP-1 GI Side Effects

December 11, 2024 15 min read Side Effects

Important Note: This article presents research analysis only. Always consult healthcare providers about managing side effects during GLP-1 treatment.

Clinical Trial Data

SURMOUNT-1 Trial Results

Based on 2,539 participants:

31%
Nausea
23%
Diarrhea
12%
Vomiting
95%
Mild/Moderate
Source: Jastreboff et al., NEJM 2022;387:205-216

Immediate Relief Strategies

Quick Relief

  • Sip ginger tea slowly
  • 5-5-5 breathing technique
  • Acupressure wrist bands
  • Small sips of clear broth

Prevention

  • Eat smaller portions
  • Avoid lying down after meals
  • Stay well hydrated
  • Time medication strategically

Warning Signs

Contact Doctor

  • Severe or persistent vomiting
  • Unable to keep liquids down
  • Signs of dehydration
  • Severe abdominal pain

Emergency Signs

  • Severe chest pain
  • Difficulty breathing
  • Extreme dizziness
  • Mental confusion

Hydration and Kidney Health

Clinical Research Findings

Research published in the Journal of Clinical Medicine (2024) highlights that proper hydration with electrolyte balance is crucial during GLP-1 treatment.

Daily Targets

  • 2-3L total fluid intake
  • 500-750mg sodium
  • 400-600mg potassium
  • 200-400mg magnesium

Recommended Sources

  • Electrolyte drinks (sugar-free)
  • Bone broth or clear soups
  • Coconut water
  • Electrolyte tablets/powders

Recommended Products

Hydration Support

Sports Recovery

Related Resources

Dose Calculator

Calculate precise medication doses

Level Plotter

Track medication levels

Fatigue Management

Energy management guide

Dehydration Guide

Hydration management guide
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